SAMHSA’s Tribal Opioid Response (TOR) program assists in addressing the overdose crisis in Tribal communities by increasing access to FDA-approved medications for the treatment of opioid use disorder, and supporting the continuum of prevention, harm reduction, treatment, and recovery support services for opioid use disorder and co-occurring substance use disorders. The TOR program also supports the full continuum of prevention, harm reduction, treatment and recovery support services for stimulant misuse and use disorders, including for cocaine and methamphetamine. Eligibility is limited to federally recognized American Indian or Alaska Native Tribe or tribal organizations. Tribes and tribal organizations may apply individually, as a consortium, or in partnership with an Urban Indian Organizations. SAMHSA anticipates distributing up to 150 awards.